Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 3/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795634 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2MIFPRNPMAOBADRA2A | |
| SCHEMBL6798898 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2MIFCYP26A1PRNPMAOA | |
| SCHEMBL6800106 | 0.90 | MAOA (0.47) | SMN1; SMN2MIFCYP26A1CYP24A1MAOA | |
| SCHEMBL6806169 | 0.88 | MAOA (0.46) | MIFCYP26A1MAOAMAOBDRD2 | |
| SCHEMBL6796533 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2MIFCYP26A1PRNPCYP24A1 | |
| SCHEMBL6799152 | 0.84 | METAP1 (0.49) | SMN1; SMN2PRNPMAOAMAOBADRA2A | |
| SCHEMBL6795670 | 0.83 | CES2 (0.45) | MIFCYP26A1MAOAMAOBCES2 | |
| SCHEMBL6800723 | 0.83 | ESR2 (0.46) | MAOAMAOBESR1ESR2 | |
| SCHEMBL6798794 | 0.82 | HTR2A (0.47) | MIFMAOAMAOBDRD2HTR2A | |
| SCHEMBL6794626 | 0.81 | METAP1 (0.51) | SMN1; SMN2PRNPMAOBADRA2AMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | MERCK & CO., INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | ESRRA, ESRRB, FSHR | SMN1; SMN2 2695/4885MIF 881/4885CYP26A1 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.