Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.77 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416557 | 0.87 | HDAC1 (0.59) | NSD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL23015300 | 0.87 | NSD2 (1.00) | NSD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL7329778 | 0.86 | ESRRG (0.65) | NSD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL6800966 | 0.85 | NSD2 (0.71) | NSD2PDK1MEN1KMT2ANPC1 | |
| SCHEMBL7236313 | 0.84 | NSD2 (0.71) | NSD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL6799435 | 0.81 | MEN1 (0.72) | NSD2PDK1PDK2PDK3PDK4 | |
| SCHEMBL2921609 | 0.80 | KMT2A (0.68) | MEN1KMT2ANPC1HSD17B1HSD17B2 | |
| SCHEMBL6799672 | 0.79 | NSD2 (0.64) | NSD2PDK1MEN1KMT2ACA12 | |
| SCHEMBL5118098 | 0.79 | NSD2 (0.63) | NSD2MEN1KMT2ANPC1CA12 | |
| SCHEMBL5317577 | 0.78 | NSD2 (0.61) | NSD2MEN1KMT2ANPC1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |