Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416641 | 0.89 | MEN1 (0.77) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6796753 | 0.85 | NSD2 (0.77) | NSD2MEN1KMT2APDK1HSD17B2 | |
| SCHEMBL6799672 | 0.84 | NSD2 (0.64) | NSD2MEN1KMT2ALIMK2PDK1 | |
| SCHEMBL23015300 | 0.83 | NSD2 (1.00) | NSD2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL16585629 | 0.82 | MEN1 (0.68) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7236313 | 0.81 | NSD2 (0.71) | NSD2MEN1KMT2APDK1HSD17B2 | |
| SCHEMBL28509474 | 0.80 | MEN1 (0.64) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6800382 | 0.79 | MCHR1 (0.55) | KMT2ASNCAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7237239 | 0.79 | MMP13 (0.73) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9416624 | 0.78 | KMT2A (0.89) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |