Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | STS | P08842 | 9/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795598 | 0.85 | MEN1 (0.60) | NSD2CA1CA2CA9STS | |
| SCHEMBL6800966 | 0.84 | NSD2 (0.71) | NSD2PDK1MEN1KMT2ALIMK2 | |
| SCHEMBL6799571 | 0.81 | CA1 (0.61) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL6799793 | 0.80 | CYP19A1 (0.64) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL6800721 | 0.80 | MEN1 (0.63) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL6796753 | 0.79 | NSD2 (0.77) | NSD2CA2CA9CYP19A1CA12 | |
| SCHEMBL6801736 | 0.79 | CA1 (0.65) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL23015300 | 0.78 | NSD2 (1.00) | NSD2PDK1MEN1KMT2ALIMK2 | |
| SCHEMBL6797851 | 0.77 | CYP19A1 (0.67) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL7236313 | 0.76 | NSD2 (0.71) | NSD2PDK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |