Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683633 | 0.85 | HSD17B10 (0.41) | CYP3A4TP53HTTPKMSMN1; SMN2 | |
| SCHEMBL2751216 | 0.82 | TSHR (0.51) | TP53HTTKMT2AFOLH1MRGPRX4 | |
| SCHEMBL4680325 | 0.81 | TSHR (0.36) | CYP3A4HTTPKMSMN1; SMN2LIG1 | |
| SCHEMBL4683622 | 0.81 | KEAP1 (0.38) | CYP3A4PKMSMN1; SMN2LIG1ALDH1A1 | |
| SCHEMBL4681122 | 0.81 | CSNK2A1 (0.39) | CYP3A4PKMSMN1; SMN2KMT2ALIG1 | |
| SCHEMBL8791448 | 0.81 | PKM (0.38) | CYP3A4PKMSMN1; SMN2LIG1ALDH1A1 | |
| SCHEMBL22799778 | 0.80 | CYP3A4 (0.50) | CYP3A4TP53HTTKMT2AFOLH1 | |
| SCHEMBL4683685 | 0.80 | SMN1; SMN2 (0.36) | CYP3A4PKMSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL9565658 | 0.79 | PKM (0.36) | CYP3A4PKMSMN1; SMN2LIG1ALDH1A1 | |
| SCHEMBL4683704 | 0.79 | GAA (0.33) | CYP3A4TP53PKMSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198790-A1 | Water-soluble triazole fungicide | SANKYO COMPANY, LIMITED (JP) | 2004-10-07 | — | — | US | disclosed |
| EP-0558959-B1 | Phosphonooxy and carbonate derivatives of taxol | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5272171-A | Phosphonooxy and carbonate derivatives of taxol | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0569281-A1 | Benzoate derivatives of taxol | Bristol-Myers Squibb Company (US) | 1993-11-10 | — | — | EP | disclosed |
| EP-0558959-A1 | Phosphonooxy and carbonate derivatives of taxol | Bristol-Myers Squibb Company (US) | 1993-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198790-A1 | Water-soluble triazole fungicide | ERG28, CYP51A1, XDH | CYP3A4 87/4885TP53 1148/4885HTT 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.