Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylbenzene SCHEMBL6796969 | 0.85 | TSHR (0.51) | HPGDXBP1TSHRPOLBALDH1A1 | |
| SCHEMBL29566931 | 0.80 | TSHR (0.63) | TSHRPOLBALDH1A1KDM4EP2RX7 | |
| SCHEMBL36590 | 0.80 | TSHR (0.63) | TSHRPOLBALDH1A1KDM4EP2RX7 | |
| Benzoyl Peroxide SCHEMBL2125048 | 0.75 | LMNA (0.55) | HPGDXBP1TSHRPOLBALDH1A1 | |
| Bicarbonate SCHEMBL11150406 | 0.73 | RAB9A (0.49) | HPGDXBP1POLBKDM4ENPC1 | |
| Acetone SCHEMBL11207944 | 0.73 | RAB9A (0.49) | HPGDXBP1POLBALDH1A1KDM4E | |
| SCHEMBL16628 | 0.73 | RAB9A (0.46) | HPGDXBP1POLBALDH1A1KDM4E | |
| SCHEMBL18614728 | 0.73 | RAB9A (0.46) | HPGDXBP1POLBALDH1A1KDM4E | |
| SCHEMBL21676265 | 0.72 | TSHR (0.53) | TSHRPOLBKDM4EP2RX7TAS1R3 | |
| SCHEMBL3829070 | 0.71 | TSHR (0.61) | TSHRPOLBALDH1A1KDM4EP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162399-A1 | impact modifier composition comprises structural units derived from: at least one silicone rubber monomer, a branched acrylate rubber monomer | GENERAL ELECTRIC COMPANY | 2004-08-19 | — | — | US | disclosed |