Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GHSR | Q92847 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801760 | 0.88 | GHSR (0.41) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6797604 | 0.78 | MAPT (0.57) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6636640 | 0.77 | GHSR (0.65) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 | |
| SCHEMBL315827 | 0.77 | GHSR (0.57) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 | |
| SCHEMBL316299 | 0.76 | KMT2A (0.57) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6642450 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 | |
| SCHEMBL316059 | 0.76 | KMT2A (0.59) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6642290 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6636462 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 | |
| SCHEMBL315998 | 0.75 | KMT2A (0.57) | SMN1; SMN2GHSRKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010005-A1 | Stereoselective process for preparing cylcohexyl amine derivatives | BARNETT CHARLES JACKSON (US) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010005-A1 | Stereoselective process for preparing cylcohexyl amine derivatives | ALKBH3, AZI2, ALKBH1 | SMN1; SMN2 2439/4885GHSR 2273/4885KMT2A 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.