Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28782135 | 0.76 | POLB (0.47) | LTA4HKCNH2SLC6A1SLC6A11MAPT | |
| SCHEMBL9142984 | 0.74 | MEN1 (0.45) | KDM4ELTA4HKCNH2MAPTRAB9A | |
| SCHEMBL27564530 | 0.73 | KDM4E (0.42) | KDM4ELTA4HSLC6A1SLC6A11 | |
| SCHEMBL28747644 | 0.71 | CHRNB4 (0.62) | KDM4E | |
| SCHEMBL27584211 | 0.70 | CHRNB4 (0.58) | KDM4E | |
| SCHEMBL8697094 | 0.70 | LTA4H (0.66) | KDM4ELTA4H | |
| SCHEMBL10285195 | 0.69 | KCNH2 (0.41) | KDM4EKCNH2MAPT | |
| SCHEMBL11197152 | 0.68 | SLC6A1 (0.70) | SLC6A1 | |
| SCHEMBL9143896 | 0.67 | OPRM1 (0.62) | KCNH2 | |
| SCHEMBL5717731 | 0.67 | HPGD (0.47) | KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815547-B2 | ANTIMICROBIAL AGENTS EFFECTIVE AGAINST STAPHYLOCOCCUS, STREPTOCOCCUS, ENTEROCOCCUS | AVENTIS PHARMA S.A. (FR) | 2004-11-09 | — | — | US | disclosed |
| US-6602884-B2 | Useful as antibiotics against Staphylococcus, Streptococcus, Enterococcus and Moraxella | AVENTIS PHARMA S.A. (FR) | 2003-08-05 | — | — | US | disclosed |