SCHEMBL6797971

SCHEMBL6797971

Cc1cccnc1NC(=O)Cc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
TRPV1 Q8NER1 7/20 0.52
KDR P35968 2/20 0.52
SMO Q99835 1/20 0.48
BDKRB1 P46663 2/20 0.47
APOB P04114 2/20 0.46
MTTP P55157 2/20 0.46
TEK Q02763 1/20 0.46
KDM4E B2RXH2 1/20 0.46
EGLN1 Q9GZT9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7160923 0.89 TRPV1 (0.48) KMT2AL3MBTL1TRPV1KDR
SCHEMBL6799294 0.85 KMT2A (0.56) KMT2ATRPV1KDRSMOAPOB
SCHEMBL6794977 0.85 KDR (0.47) TRPV1KDRSMOBDKRB1APOB
SCHEMBL6795709 0.83 MEN1 (0.59) KMT2AL3MBTL1SMOAPOBMTTP
SCHEMBL6913405 0.82 MEN1 (0.59) KMT2AAPOBMTTPKDM4E
SCHEMBL6794043 0.81 SMO (0.61) KMT2AL3MBTL1TRPV1KDRSMO
SCHEMBL6793184 0.81 KMT2A (0.58) KMT2AAPOBMTTPKDM4E
SCHEMBL6792294 0.81 FFAR2 (0.49) TRPV1KDRSMOAPOBMTTP
SCHEMBL6792281 0.80 SMO (0.62) TRPV1KDRSMOAPOBMTTP
SCHEMBL6798808 0.79 KDR (0.56) KDRSMOAPOBMTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 KMT2A 2457/4885L3MBTL1 1793/4885TRPV1 3714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.