Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797971 | 0.89 | KMT2A (0.55) | TRPV1KDRKMT2AL3MBTL1 | |
| SCHEMBL7085005 | 0.82 | MEN1 (0.59) | KMT2AMEN1NPC1RAB9ARXFP1 | |
| SCHEMBL7084265 | 0.81 | KMT2A (0.59) | KMT2AMEN1NPC1RAB9ARXFP1 | |
| SCHEMBL7081600 | 0.79 | SORT1 (0.53) | KDRKMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL7086991 | 0.78 | SMO (0.48) | TRPV1KMT2ARXFP1ALDH1A1LMNA | |
| SCHEMBL7086952 | 0.77 | PLG (0.53) | NPC1RAB9ARXFP1LMNALRRK2 | |
| SCHEMBL7079790 | 0.77 | S1PR1 (0.51) | NPC1RAB9ARXFP1LMNARORC | |
| SCHEMBL7086824 | 0.76 | LMNA (0.48) | TRPV1KDRKMT2AL3MBTL1MEN1 | |
| SCHEMBL7087226 | 0.76 | SMO (0.49) | TRPV1KDRKMT2AL3MBTL1MEN1 | |
| SCHEMBL7080756 | 0.75 | LMNA (0.52) | TRPV1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |