Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | HAT1 | O14929 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802479 | 0.88 | CTSS (0.43) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL6808909 | 0.79 | SMN1; SMN2 (0.38) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6803422 | 0.77 | CTSS (0.52) | RAB9ANPC1SMN1; SMN2LMNAEPHX1 | |
| SCHEMBL6807801 | 0.75 | KCNA5 (0.39) | SMN1; SMN2TSHRHIF1AMEN1KMT2A | |
| SCHEMBL6808965 | 0.73 | TSHR (0.47) | RAB9ANPC1SMN1; SMN2TSHREPHX2 | |
| SCHEMBL14873381 | 0.72 | KCNA5 (0.42) | SMN1; SMN2TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12061526 | 0.71 | TAAR1 (0.40) | RAB9ANPC1SMN1; SMN2TAAR1LMNA | |
| SCHEMBL20217274 | 0.70 | KCNA5 (0.41) | SMN1; SMN2TP53TSHRSLC6A2SLC6A4 | |
| SCHEMBL9782267 | 0.69 | ADRB2 (0.51) | OPRK1LMNATSHRADRB2SLC6A4 | |
| SCHEMBL6180760 | 0.69 | NPC1 (0.47) | RAB9ANPC1ALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | OPRK1 140/4885RAB9A 1163/4885NPC1 2721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.