Bromide

Bromide

SCHEMBL679805

CC[P+](CC)(CC)c1ccccc1.[Br-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.43
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.39
ESR1 P03372 1/20 0.36
TRPA1 O75762 1/20 0.35
TSHR P16473 2/20 0.34
MIF P14174 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAOA P21397 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
SNCA P37840 1/20 0.33
PSIP1 O75475 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2965186 0.94 HIF1A (0.43) HIF1ALMNATP53ESR1TRPA1
SCHEMBL9752172 0.94 HIF1A (0.43) HIF1ALMNATP53ESR1TRPA1
Water SCHEMBL2822588 0.94 HIF1A (0.43) HIF1ALMNATP53ESR1TRPA1
Iodide SCHEMBL5085335 0.94 HIF1A (0.43) HIF1ALMNATP53ESR1TRPA1
Fluoride Ion SCHEMBL4618615 0.94 HIF1A (0.43) HIF1ALMNATP53ESR1TRPA1
SCHEMBL8206187 0.84 LMNA (0.39) HIF1ALMNAMEN1KMT2AALDH1A1
SCHEMBL9752213 0.84 HIF1A (0.36) HIF1ALMNATP53ESR1TSHR
Bromide SCHEMBL8559535 0.82 HIF1A (0.39) HIF1ALMNATP53ESR1TRPA1
Oxalic Acid SCHEMBL1049238 0.82 CES2 (0.41) LMNATSHRMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL5180858 0.80 HIF1A (0.42) HIF1ALMNATP53ESR1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112646155-B Amide-modified polyester resin for powder coating and powder coating 浙江光华科技股份有限公司 2022-09-27 CN claimed
CN-112646155-A Amide-modified polyester resin for powder coating and powder coating 浙江光华科技股份有限公司 2021-04-13 CN claimed
EP-2954011-A1 ULTRA LOW CURE POWDER COATING Valspar Sourcing, Inc. (US) 2015-12-16 EP claimed
US-20150024194-A1 ULTRA LOW CURE POWDER COATINGS VALSPAR SOURCING, INC. (US) 2015-01-22 US claimed
WO-2014123534-A1 ULTRA LOW CURE POWDER COATING VALSPAR SOURCING, INC. (US) 2014-08-14 WO claimed
CN-101395237-B Improvements in and relating to powder coating compositions crosslinked with non-cyanurate polyepoxides HEXION SPECIALTY CHEMICALS RES 2012-04-04 CN claimed
US-20120004373-A1 POWDER COATING COMPOSITIONS CROSS-LINKED WITH NON CYANURATE POLYEPOXIDES HEXION INC. (FORMERLY KNOWN AS MOMENTIVE SPECIALTY CHEMICALS INC.) 2012-01-05 US claimed
CN-101395237-A Improvements in and relating to powder coating compositions crosslinked with non-cyanurate polyepoxides HEXION SPECIALTY CHEMICALS RES (US) 2009-03-25 CN claimed
EP-1920016-A2 IMPROVEMENTS IN AND RELATING TO POWDER COATING COMPOSITIONS CROSS-LINKED WITH NON CYANURATE POLYEPOXIDES Hexion Specialty Chemicals Research Belgium S.A. (BE) 2008-05-14 EP claimed
WO-2007025664-A2 IMPROVEMENTS IN AND RELATING TO POWDER COATING COMPOSITIONS CROSS-LINKED WITH NON CYANURATE POLYEPOXIDES HEXION SPECIALTY CHEMICALS RESEARCH BELGIUM S.A. (BE) 2007-03-08 WO claimed
EP-0918810-B1 LOW TEMPERATURE CURE CARBOXYL TERMINATED POLYESTERS RESOLUTION SPECIALTY MATERIALS (US) 2005-03-09 EP claimed
US-6284845-B1 POWDERED COATING COMPOSITION WHICH INCLUDES A CARBOXYL TERMINATED POLYESTER, EPOXY COMPOUNDS AND AN ONIUM CATALYST OR BETA-HYDROXYALKYLAMIDE MCWHORTER TECHNOLOGIES 2001-09-04 US claimed
EP-0918810-A4 LOW TEMPERATURE CURE CARBOXYL TERMINATED POLYESTERS MCWHORTER TECHNOLOGIES INC (US) 2001-05-16 EP claimed
EP-0918810-A1 LOW TEMPERATURE CURE CARBOXYL TERMINATED POLYESTERS McWHORTER TECHNOLOGIES, Inc. (US) 1999-06-02 EP claimed
WO-1998006772-A1 LOW TEMPERATURE CURE CARBOXYL TERMINATED POLYESTERS MCWHORTER TECHNOLOGIES, INC. (US) 1998-02-19 WO claimed
US-5637654-A ONIUM CURING CATALYST; LOW TEMPERATURE CURING, HARDNESS, FLEXIBILITY MCWHORTER TECHNOLOGIES (US) 1997-06-10 US claimed
CN-112646155-B Amide-modified polyester resin for powder coating and powder coating 浙江光华科技股份有限公司 2022-09-27 CN disclosed
CN-110770274-B Powder coating compositions containing aromatic polymerizates of aromatic isocyanate production processes 科思创有限公司 2022-02-22 CN disclosed
EP-0402998-A1 Resin composition suitable for substantially solvent-free paint compositions DSM N.V. (NL) 1990-12-19 EP disclosed
US-3992370-A 1,1-Dichloro-1a,1b-dihydrodibenzo(b,f)cycloprop(d)azepine-6(1H)-carboxaldehyde TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-11-16 US disclosed