SCHEMBL6798073

SCHEMBL6798073

CC(C)(C)OC(=O)N(CCc1ccc(NS(=O)(=O)O)cc1)S(=O)(=O)c1ccccc1F

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTPRB P23467 12/20 0.44
PTPN11 Q06124 1/20 0.44
PTPN1 P18031 3/20 0.42
PTPN2 P17706 2/20 0.42
PTPRA P18433 1/20 0.42
PTPRC P08575 1/20 0.41
PTPRG P23470 1/20 0.41
ACP1 P24666 1/20 0.41
PTGER2 P43116 2/20 0.38
KCNA5 P22460 1/20 0.38
KCNH2 Q12809 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6803115 0.85 KCNA5 (0.41) PTGER2KCNA5MEN1KMT2A
SCHEMBL6803479 0.83 PTPRB (0.45) PTPRBPTPN11PTPN1PTPN2PTPRA
SCHEMBL6807936 0.82 MMP1 (0.42) PTPN1KCNH2KMT2A
SCHEMBL6796826 0.81 PTPRB (0.45) PTPRBPTPN11MEN1KMT2A
SCHEMBL7063146 0.72 STAT5B (0.47) MEN1KMT2A
SCHEMBL4880111 0.71 CA12 (0.45) MEN1KMT2A
SCHEMBL6802181 0.68 PTPRB (0.60) PTPRBPTPN1PTPN2PTPRA
SCHEMBL6807428 0.68 PTGER2 (0.41) PTGER2
SCHEMBL5280924 0.67 LTB4R (0.51) KCNH2
SCHEMBL6795785 0.67 PTPRB (0.51) PTPRBPTPN11PTPN1PTPN2PTPRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO claimed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US claimed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE PTPRB 13/4885PTPN11 31/4885PTPN1 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.