Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12758368 | 0.82 | ALDH1A1 (0.51) | ALOX15TSHRALOX12HIF1AHSD17B10 | |
| SCHEMBL23584387 | 0.81 | ALOX12 (0.66) | ALOX15TSHRALOX12HIF1AHSD17B10 | |
| SCHEMBL20091584 | 0.79 | ALDH1A1 (0.55) | ALOX15TSHRALOX12HIF1AHSD17B10 | |
| SCHEMBL8761463 | 0.78 | TSHR (0.66) | ALOX15TSHRALOX12HIF1AHSD17B10 | |
| SCHEMBL14252079 | 0.77 | HIF1A (0.59) | ALOX15TSHRALOX12HIF1AHSD17B10 | |
| SCHEMBL681064 | 0.77 | HSD17B10 (0.38) | ALOX15TSHRALOX12HSD17B10CYP3A4 | |
| SCHEMBL5173922 | 0.76 | TSHR (1.00) | ALOX15TSHRALOX12HIF1AHSD17B10 | |
| SCHEMBL18647 | 0.76 | TSHR (1.00) | ALOX15TSHRALOX12HIF1AHSD17B10 | |
| SCHEMBL679893 | 0.76 | TSHR (0.58) | ALOX15TSHRALOX12HIF1AHSD17B10 | |
| SCHEMBL25898 | 0.75 | ALDH1A1 (0.50) | ALOX15TSHRALOX12HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067497-B2 | Flame-retardant for engineering thermoplastic applications | BROMINE COMPOUNDS LTD. (IL) | 2011-11-29 | — | — | US | disclosed |