Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 1/20 | 0.50 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2697142 | 0.82 | ALDH1A1 (0.69) | NPC1RAB9AALDH1A1TRPM5NPSR1 | |
| SCHEMBL8736604 | 0.81 | TDP1 (0.53) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL6585008 | 0.80 | FDPS (0.55) | NPC1RAB9AALDH1A1TRPM5NPSR1 | |
| SCHEMBL25798826 | 0.79 | CETP (0.59) | ALDH1A1CETPMAPTKDM4ELMNA | |
| SCHEMBL4652385 | 0.79 | CETP (0.53) | ALDH1A1CETPMAPTSMN1; SMN2KDM4E | |
| SCHEMBL12259157 | 0.75 | FDPS (0.71) | NPC1RAB9AALDH1A1NPSR1MAPT | |
| SCHEMBL29955595 | 0.75 | ALDH1A1 (0.61) | ALDH1A1RXFP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL13819488 | 0.75 | ALDH1A1 (0.61) | ALDH1A1RXFP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL2432443 | 0.74 | ALDH1A1 (0.66) | NPC1RAB9AALDH1A1RXFP1NPSR1 | |
| SCHEMBL29957052 | 0.74 | ALDH1A1 (0.66) | NPC1RAB9AALDH1A1RXFP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248850-A1 | Compounds for the treatment of HIV infection | KEMIA, INC. | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248850-A1 | Compounds for the treatment of HIV infection | CCR5, CD4, HAVCR2 | NPC1 29/4885RAB9A 2629/4885ALDH1A1 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.