Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | APOB | P04114 | 3/20 | 0.50 |
| ▸ | MTTP | P55157 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800223 | 0.90 | ADRB1 (0.53) | HIF1AEPAS1ADRB1ADRB3APOB | |
| SCHEMBL6793692 | 0.88 | HIF1A (0.53) | HIF1AEPAS1ADRB1ADRB3APOB | |
| SCHEMBL6792412 | 0.86 | ADRB3 (0.54) | HIF1AEPAS1ADRB1ADRB3APOB | |
| SCHEMBL7085416 | 0.86 | ADRB3 (0.48) | HIF1AEPAS1ADRB1ADRB3HTT | |
| SCHEMBL6793814 | 0.84 | SMO (0.59) | APOBMTTPHTTALDH1A1KDR | |
| SCHEMBL6788109 | 0.83 | MTTP (0.56) | APOBMTTPALDH1A1SMN1; SMN2PTGS1 | |
| SCHEMBL6792347 | 0.83 | NAMPT (0.54) | HIF1AEPAS1APOBMTTPHTT | |
| SCHEMBL6787993 | 0.83 | MTTP (0.54) | APOBMTTPALDH1A1SMN1; SMN2PTGS1 | |
| SCHEMBL6791009 | 0.82 | TRPV1 (0.55) | APOBMTTPALDH1A1KDRSMN1; SMN2 | |
| SCHEMBL6794895 | 0.82 | KDR (0.57) | ADRB1ADRB3APOBMTTPHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | HIF1A 4361/4885EPAS1 2569/4885ADRB1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.