Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910592 | 0.83 | HPGD (1.00) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6798736 | 0.78 | L3MBTL1 (0.63) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9529930 | 0.77 | MAOB (0.71) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL26485873 | 0.76 | LMNA (0.73) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9528898 | 0.76 | ALDH1A1 (0.70) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5998349 | 0.75 | SMN1; SMN2 (0.75) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL14434222 | 0.75 | ALDH1A1 (1.00) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL11647542 | 0.75 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL11643864 | 0.75 | ALDH1A1 (0.70) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5449567 | 0.74 | IDO1 (0.78) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |