Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | ACACA | Q13085 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679991 | 0.89 | PLK1 (0.59) | LMNAPLK1TP53SCN3ANPC1 | |
| SCHEMBL680286 | 0.85 | PGR (0.60) | BCL2L1MCL1TP53NPC1RAB9A | |
| SCHEMBL7985860 | 0.85 | KAT6A (0.61) | LMNAMAPK1L3MBTL1TP53SCN3A | |
| SCHEMBL7990905 | 0.85 | PLK1 (0.65) | LMNAPLK1TP53SCN3ANPC1 | |
| SCHEMBL679866 | 0.83 | SCN9A (0.55) | LMNABCL2L1MCL1SCN3AMAPT | |
| SCHEMBL680466 | 0.83 | EZH2 (0.54) | MAPK1L3MBTL1BCL2L1MCL1TP53 | |
| SCHEMBL678903 | 0.82 | BCL2L1 (0.52) | L3MBTL1BCL2L1MCL1NPC1RAB9A | |
| SCHEMBL678831 | 0.82 | BCL2L1 (0.52) | BCL2L1MCL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16319187 | 0.81 | MAPK14 (0.56) | LMNABCL2L1MCL1KAT6ANPC1 | |
| SCHEMBL679923 | 0.81 | SCN3A (0.47) | LMNATP53SCN3AKAT6ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |
| US-20120010207-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010207-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | ACACB 4480/4885ACACA 3742/4885RECQL 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.