Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13182691 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL54839 | 0.81 | LMNA (0.53) | CYP3A4BLMPMP22HIF1AESRRG | |
| N',N'-Dimethylbenzohydrazide SCHEMBL952727 | 0.80 | POLB (0.56) | CYP3A4ALDH1A1MAPTKMT2ACA12 | |
| SCHEMBL21164232 | 0.78 | CES2 (0.55) | — | |
| SCHEMBL13006679 | 0.78 | HPGD (0.55) | ESRRGALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2996638 | 0.77 | ALDH1A1 (0.59) | GFERMPOCYP3A4ALDH1A1MAPT | |
| SCHEMBL22635864 | 0.77 | HDAC1 (0.39) | CYP3A4ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL24370842 | 0.76 | TAS1R3 (0.51) | MPOESRRGALDH1A1MAPTKMT2A | |
| SCHEMBL159659 | 0.75 | HDAC2 (0.67) | GFERMPOCYP3A4KDM5ABLM | |
| SCHEMBL29202850 | 0.74 | GFER (0.65) | GFERMPOCYP3A4KDM5ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |