Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 2/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272760 | 1.00 | MLYCD (0.68) | MLYCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9337665 | 0.93 | MLYCD (0.76) | MLYCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL6263516 | 0.93 | MLYCD (0.76) | MLYCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL15482261 | 0.86 | MLYCD (0.68) | MLYCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL20764458 | 0.86 | MLYCD (0.68) | MLYCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31311100 | 0.86 | MLYCD (0.68) | MLYCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL899585 | 0.85 | DEGS1 (0.75) | MEN1NPC1RAB9AKMT2ADEGS1 | |
| SCHEMBL900928 | 0.85 | DEGS1 (0.75) | MEN1NPC1RAB9AKMT2ADEGS1 | |
| SCHEMBL8420639 | 0.85 | DEGS1 (0.75) | MEN1NPC1RAB9AKMT2ADEGS1 | |
| SCHEMBL20379456 | 0.85 | MEN1 (0.73) | MLYCDMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |