Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667326 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TDP1ADAMTS4CA2CA12 | |
| SCHEMBL2961408 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TDP1MEN1KMT2ANPC1 | |
| SCHEMBL3335019 | 0.77 | ALDH1A1 (0.69) | ALDH1A1TDP1ADAMTS4HRH2HRH1 | |
| SCHEMBL14596863 | 0.76 | ALDH1A1 (0.56) | ALDH1A1TDP1CA2MEN1KMT2A | |
| SCHEMBL14596865 | 0.76 | CA1 (0.61) | ALDH1A1CA2CA12MEN1KMT2A | |
| SCHEMBL27545486 | 0.75 | CA2 (0.59) | ADAMTS4CA2CA12MEN1KMT2A | |
| SCHEMBL8697204 | 0.74 | ALDH1A1 (0.65) | ALDH1A1TDP1ADAMTS4PTPN1MEN1 | |
| SCHEMBL9311171 | 0.74 | ALDH1A1 (0.65) | ALDH1A1TDP1ADAMTS4DRD1 | |
| SCHEMBL10451884 | 0.74 | ALDH1A1 (0.69) | ALDH1A1TDP1ADAMTS4PTPN1MEN1 | |
| SCHEMBL7773844 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TDP1ADAMTS4HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |