Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.66 |
| ▸ | CA9 | Q16790 | 10/20 | 0.66 |
| ▸ | CA1 | P00915 | 9/20 | 0.66 |
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172136 | 0.81 | CA1 (0.51) | CA2CA9CA1CA12CYP19A1 | |
| SCHEMBL7263619 | 0.80 | CA2 (1.00) | CA2CA9CA1CA12KIF11 | |
| SCHEMBL29360677 | 0.75 | CYP2A6 (0.88) | CA2CA9CA1CA12CYP19A1 | |
| SCHEMBL13907273 | 0.75 | CYP2A6 (0.88) | CA2CA9CA1CA12CYP19A1 | |
| SCHEMBL24534338 | 0.75 | CYP2A6 (0.88) | CA2CA9CA1CA12CYP19A1 | |
| SCHEMBL7658570 | 0.74 | CA2 (0.59) | CA2CA9CA1CA12CYP19A1 | |
| SCHEMBL27615591 | 0.73 | MKNK1 (0.63) | CA2CA9CA1CA12CYP19A1 | |
| SCHEMBL2059681 | 0.73 | CYP11B2 (0.72) | CYP19A1CYP3A4CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL22778252 | 0.73 | CYP11B2 (0.72) | CYP19A1CYP3A4CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL18194403 | 0.73 | CA2 (0.73) | CA2CA9CA1CA12CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |