Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642320 | 0.88 | MAPT (0.43) | MAPTTP53POLBGHSRTSHR | |
| SCHEMBL6797604 | 0.88 | MAPT (0.57) | MAPTTP53POLBGHSRTSHR | |
| SCHEMBL6644456 | 0.81 | ACACB (0.40) | MAPTTP53POLBGHSRALDH1A1 | |
| SCHEMBL6774056 | 0.81 | KMT2A (0.42) | POLBKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6638957 | 0.81 | KMT2A (0.42) | POLBKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6801760 | 0.79 | GHSR (0.41) | MAPTTP53POLBGHSRALDH1A1 | |
| SCHEMBL5774786 | 0.78 | ALDH1A1 (0.56) | MAPTTP53POLBTSHRKDM4E | |
| SCHEMBL7509719 | 0.78 | GHSR (0.45) | MAPTTP53POLBGHSRKDM4E | |
| SCHEMBL6636640 | 0.78 | GHSR (0.65) | MAPTTP53POLBGHSRTSHR | |
| SCHEMBL6640564 | 0.77 | POLB (0.46) | MAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176405-A1 | Methods and compounds for inhibitting MRP1 | KROIN JULIAN (US) | 2004-09-09 | — | — | US | disclosed |
| US-20040010005-A1 | Stereoselective process for preparing cylcohexyl amine derivatives | BARNETT CHARLES JACKSON (US) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176405-A1 | Methods and compounds for inhibitting MRP1 | ABCC1, ABCB11, ABCB1 | MAPT 4012/4885TP53 2033/4885POLB 2053/4885 |
| US-20040010005-A1 | Stereoselective process for preparing cylcohexyl amine derivatives | ALKBH3, AZI2, ALKBH1 | MAPT 4576/4885TP53 4705/4885POLB 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.