Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6801594 | 0.99 | POLB (0.55) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL593247 | 0.78 | POLB (0.58) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL591955 | 0.78 | POLB (0.58) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL230157 | 0.77 | POLB (0.84) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL9039049 | 0.76 | POLB (0.66) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL594026 | 0.75 | ALDH1A1 (0.62) | POLBNPC1RAB9ADDAH1PDE10A | |
| SCHEMBL8948422 | 0.74 | NPC1 (0.71) | POLBNPC1RAB9ACHRM1PDE10A | |
| SCHEMBL6801751 | 0.73 | POLB (0.57) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL7854448 | 0.73 | POLB (0.92) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL7006523 | 0.73 | POLB (1.00) | POLBNPC1RAB9ACHRM1DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004066999-A1 | COMPOSITIONS CONTAINING 2, 2’ -METHYLENEBISBENZIMIDAZOLE DERIVATIVES FOR TREATING ISCHEMIA-RELATED NEURONAL DAMAGE | ELAN PHARMACEUTICALS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |