SCHEMBL680187

SCHEMBL680187

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
SMN1; SMN2 Q16637 3/20 0.43
LMNA P02545 3/20 0.42
HSD17B10 Q99714 3/20 0.42
POLB P06746 3/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPT P10636 2/20 0.42
HPGD P15428 2/20 0.42
HTT P42858 2/20 0.42
TSHR P16473 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40
MAT2A P31153 2/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
NR1I2 O75469 1/20 0.40
AHR P35869 1/20 0.40
MAPK1 P28482 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
USP2 O75604 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12455274 0.95 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2LMNAHSD17B10POLB
SCHEMBL19084770 0.90 ACHE (0.43) ALDH1A1SMN1; SMN2LMNAHSD17B10POLB
SCHEMBL17755594 0.88 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2LMNAHSD17B10POLB
SCHEMBL19862095 0.88 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2LMNAHSD17B10POLB
SCHEMBL680518 0.86 MAT2A (0.46) ALDH1A1SMN1; SMN2LMNAHSD17B10POLB
SCHEMBL25906883 0.85 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2LMNAHSD17B10POLB
SCHEMBL19862114 0.81 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2LMNAHSD17B10POLB
SCHEMBL28949358 0.80 MAPT (0.42) ALDH1A1SMN1; SMN2POLBKDM4EMAPT
SCHEMBL17952843 0.79 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2LMNAPOLBKDM4E
SCHEMBL28728317 0.79 MEN1 (0.43) ALDH1A1SMN1; SMN2HSD17B10POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111961036-A Synthesis and application of different alkyl substituted carbazole/pyridine bipolar host materials 淮阴师范学院 2020-11-20 CN disclosed
US-8053547-B2 Conjugated polymers and blends containing carbazole, representation and use thereof MERCK PATENT GMBH (DE) 2011-11-08 US disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed
CN-1609101-B Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LAB 2010-05-26 CN disclosed
EP-1592729-B1 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF MERCK PATENT GMBH (DE) 2008-04-23 EP disclosed
US-7314769-B2 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-01 US disclosed
US-6998492-B2 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-02-14 US disclosed
CN-1609101-A Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LAB (JP) 2005-04-27 CN disclosed
US-20050033054-A1 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2005-02-10 US disclosed
US-20040230061-A1 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2004-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050033054-A1 Organometallic complex and light-emitting element containing the same BCKDK, CCNK, CDK20 ALDH1A1 355/4885SMN1; SMN2 4825/4885LMNA 2107/4885
US-20040230061-A1 Organometallic complex and light-emitting element containing the same NR0B1, BCKDK, NR4A1 ALDH1A1 256/4885SMN1; SMN2 4808/4885LMNA 2250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.