Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.49 |
| ▸ | ITGAV | P06756 | 17/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640260 | 0.85 | ITGB3 (0.43) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6802240 | 0.85 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6802237 | 0.85 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL4641449 | 0.85 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6804912 | 0.85 | ITGB3 (0.45) | ITGB3ITGAV | |
| SCHEMBL6811574 | 0.84 | ITGB3 (0.45) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6811105 | 0.83 | CNR1 (0.44) | ITGB3ITGAV | |
| SCHEMBL6810562 | 0.80 | ITGB3 (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL6810547 | 0.78 | ITGB3 (0.40) | ITGB3ITGAV | |
| SCHEMBL6805979 | 0.76 | CNR1 (0.41) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |