Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801113 | 0.79 | HSD11B1 (0.31) | — | |
| SCHEMBL7482047 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL6802461 | 0.75 | MAPT (0.32) | — | |
| SCHEMBL7162480 | 0.72 | GRIN2D (0.46) | — | |
| SCHEMBL6830524 | 0.66 | ALOX5 (0.30) | — | |
| SCHEMBL4248928 | 0.64 | DDB1 (0.35) | DDB1CRBN | |
| SCHEMBL12710695 | 0.64 | GRIN2D (0.32) | — | |
| SCHEMBL9951769 | 0.63 | ALDH1A1 (0.36) | — | |
| SCHEMBL28104 | 0.62 | GRIN2D (0.55) | — | |
| SCHEMBL4541131 | 0.62 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128271-A1 | N-benzenesulfonyl l-proline compounds as bradykinin antagonists | PFIZER INC. | 2002-09-12 | — | — | US | claimed |
| US-6734306-B2 | USEFUL IN THE TREATMENT OF INFLAMMATION, ASTHMA, ALLERGIC RHINITIS, PAIN OR THE LIKE | PFIZER, INC. | 2004-05-11 | — | — | US | disclosed |
| US-20020128271-A1 | N-benzenesulfonyl l-proline compounds as bradykinin antagonists | PFIZER INC. | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128271-A1 | N-benzenesulfonyl l-proline compounds as bradykinin antagonists | BDKRB1, HRH2, BDKRB2 | DDB1 1774/4885CRBN 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.