SCHEMBL680246

SCHEMBL680246

Cc1ccc(S(=O)(=O)C(C)NC(C)S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
CA2 P00918 7/20 0.47
CA1 P00915 6/20 0.47
CA9 Q16790 4/20 0.47
CA7 P43166 2/20 0.47
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
MMP13 P45452 1/20 0.47
CA12 O43570 3/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
GBA1 P04062 1/20 0.46
DNMT1 P26358 1/20 0.45
TLR9 Q9NR96 1/20 0.45
ALDH1A1 P00352 7/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9956124 0.85 GAA (0.52) GAASMN1; SMN2CA2CA1CA9
SCHEMBL3442044 0.80 TLR9 (0.44) GAASMN1; SMN2CA2CA1CA9
SCHEMBL7092154 0.80 GAA (0.52) GAASMN1; SMN2CA2CA1CA9
SCHEMBL1149214 0.79 GAA (0.56) GAASMN1; SMN2CA2CA1CA9
SCHEMBL178444 0.79 GAA (0.56) GAASMN1; SMN2CA2CA1CA9
SCHEMBL30896660 0.79 GAA (0.56) GAASMN1; SMN2CA2CA1CA9
SCHEMBL9385444 0.77 GAA (0.54) GAASMN1; SMN2CA2CA1CA9
SCHEMBL26343853 0.77 GAA (0.59) GAASMN1; SMN2CA2CA1CA9
SCHEMBL15478776 0.76 GAA (0.52) GAASMN1; SMN2CA2CA1CA9
SCHEMBL5346463 0.76 GAA (0.52) GAASMN1; SMN2CA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9713627-B2 Pathogen-inactivated red blood cell compositions CERUS CORPORATION (US) 2017-07-25 US claimed
US-20150157665-A1 PATHODEN-INACTIVATED RED BLOOD CELL COMPOSITIONS CERUS CORPORATION (US) 2015-06-11 US claimed
US-20230408490-A1 SYSTEMS AND METHODS FOR TESTING AND SCREENING USING COMPOUND BOUND SUBSTRATES CERUS CORPORATION 2023-12-21 US disclosed
US-20230263833-A1 COMPOSITIONS AND METHODS FOR PREPARATION OF RED BLOOD CELLS CERUS CORPORATION 2023-08-24 US disclosed
US-20220031917-A1 METHODS AND KITS FOR PREPARING PATHOGEN-INACTIVATED WHOLE BLOOD MIDCAP FINANCIAL TRUST 2022-02-03 US disclosed
CN-113271975-A Method and kit for preparing pathogen inactivated whole blood 塞鲁斯公司 2021-08-17 CN disclosed
EP-3852817-A1 METHODS AND KITS FOR PREPARING PATHOGEN-INACTIVATED WHOLE BLOOD Cerus Corporation (US) 2021-07-28 EP disclosed
WO-2020061537-A1 METHODS AND KITS FOR PREPARING PATHOGEN-INACTIVATED WHOLE BLOOD CERUS CORPORATION (US) 2020-03-26 WO disclosed
EP-3562493-A1 COMPOSITIONS AND METHODS FOR PREPARATION OF RED BLOOD CELLS Cerus Corporation (US) 2019-11-06 EP disclosed
EP-3559665-A1 SYSTEMS AND METHODS FOR TESTING AND SCREENING USING COMPOUND BOUND SUBSTRATES Cerus Corporation (US) 2019-10-30 EP disclosed
US-20190321407-A1 COMPOSITIONS AND METHODS FOR PREPARATION OF RED BLOOD CELLS MIDCAP FINANCIAL TRUST 2019-10-24 US disclosed
US-8900805-B2 Quenching methods for red blood cell pathogen inactivation CERUS CORPORATION (US) 2014-12-02 US disclosed
EP-1838355-B1 IMPROVED QUENCHING METHODS FOR RED BLOOD CELL INACTIVATION PROCESS CERUS CORP (US) 2013-08-14 EP disclosed
US-20110286987-A1 QUENCHING METHODS FOR RED BLOOD CELL PATHOGEN INACTIVATION MIDCAP FINANCIAL TRUST 2011-11-24 US disclosed
EP-2285210-A2 IMPROVED QUENCHING METHODS FOR RED BLOOD CELL PATHOGEN INACTIVATION Cerus Corporation (US) 2011-02-23 EP disclosed
US-7655392-B2 Reducing of undesired side reactions upon treating a red blood cell composition with a pathogen inactivating compound comprising a nucleic acid binding ligand and an electrophilic group CERUS CORPORATION (US) 2010-02-02 US disclosed
WO-2009126786-A2 IMPROVED QUENCHING METHODS FOR RED BLOOD CELL PATHOGEN INACTIVATION CERUS CORPORATION (US) 2009-10-15 WO disclosed
EP-1838355-A1 IMPROVED QUENCHING METHODS FOR RED BLOOD CELL INACTIVATION PROCESS Cerus Corporation (US) 2007-10-03 EP disclosed
US-20060115466-A1 Reducing of undesired side reactions upon treating a red blood cell composition with a pathogen inactivating compound comprising a nucleic acid binding ligand and an electrophilic group MIDCAP FINANCIAL TRUST 2006-06-01 US disclosed
WO-2006050328-A1 IMPROVED QUENCHING METHODS FOR RED BLOOD CELL INACTIVATION PROCESS CERUS CORPORATION (US) 2006-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060115466-A1 Reducing of undesired side reactions upon treating a red blood cell composition with a pathogen inactivating compound comprising a nucleic acid binding ligand and an electrophilic group CD47, APEX1, SAMHD1 GAA 637/4885SMN1; SMN2 3328/4885CA2 930/4885
US-20150157665-A1 PATHODEN-INACTIVATED RED BLOOD CELL COMPOSITIONS CD47, CD4, CD209 GAA 1784/4885SMN1; SMN2 3687/4885CA2 3301/4885
US-20220031917-A1 METHODS AND KITS FOR PREPARING PATHOGEN-INACTIVATED WHOLE BLOOD HBG1, THPO, HBG2 GAA 339/4885SMN1; SMN2 3008/4885CA2 4305/4885
US-20110286987-A1 QUENCHING METHODS FOR RED BLOOD CELL PATHOGEN INACTIVATION G6PD, CD47, CD14 GAA 340/4885SMN1; SMN2 4303/4885CA2 926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.