Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.77 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.77 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.77 |
| ▸ | WDR5 | P61964 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 7/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.69 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.68 |
| ▸ | ACLY | P53396 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CCR2 | P41597 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775395 | 0.88 | WDR5 (0.68) | ERBB2HSP90AA1HSP90AB1WDR5GAA | |
| SCHEMBL12838827 | 0.87 | ERBB2 (1.00) | ERBB2HSP90AA1HSP90AB1WDR5GAA | |
| SCHEMBL3786165 | 0.85 | ERBB2 (0.73) | ERBB2HSP90AA1HSP90AB1ALDH1A1HTT | |
| SCHEMBL29858930 | 0.84 | WDR5 (1.00) | ERBB2HSP90AA1HSP90AB1WDR5GAA | |
| SCHEMBL28878201 | 0.84 | WDR5 (0.64) | ERBB2HSP90AA1HSP90AB1WDR5GAA | |
| SCHEMBL5801599 | 0.83 | ERBB2 (0.67) | ERBB2HSP90AA1HSP90AB1GAAALDH1A1 | |
| SCHEMBL9345894 | 0.82 | GAA (1.00) | ERBB2HSP90AA1HSP90AB1GAAGFER | |
| SCHEMBL3810580 | 0.81 | ACLY (0.70) | ERBB2HSP90AA1HSP90AB1ACLYCCR2 | |
| SCHEMBL12839891 | 0.81 | HSD17B2 (0.64) | ERBB2HSP90AA1HSP90AB1WDR5GAA | |
| SCHEMBL12840705 | 0.81 | GAA (0.69) | ERBB2HSP90AA1HSP90AB1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | claimed |
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | claimed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | claimed |
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | disclosed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | disclosed |