Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045233 | 0.89 | KDM4E (0.46) | ALDH1A1KDM4ENPC1MAPTPKM | |
| SCHEMBL5047614 | 0.89 | KDM4E (0.46) | ALDH1A1KDM4ENPC1MAPTPKM | |
| SCHEMBL5044424 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1MAPTPKM | |
| SCHEMBL5039990 | 0.82 | SPHK1 (0.41) | ALDH1A1KDM4ENPC1MAPTPKM | |
| SCHEMBL5044858 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4ENPC1MAPTPKM | |
| SCHEMBL5045658 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4ENPC1MAPTPKM | |
| SCHEMBL5044867 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPC1MAPTPKM | |
| SCHEMBL6806996 | 0.77 | SPHK1 (0.42) | ALDH1A1KDM4ENPC1MAPTPKM | |
| SCHEMBL1855102 | 0.77 | SPHK1 (0.42) | ALDH1A1KDM4ENPC1MAPTPKM | |
| SCHEMBL5049461 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1KDM4ENPC1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |