Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 8/20 | 0.57 |
| ▸ | MMP2 | P08253 | 6/20 | 0.57 |
| ▸ | MMP7 | P09237 | 3/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 7/20 | 0.55 |
| ▸ | MMP1 | P03956 | 5/20 | 0.55 |
| ▸ | FCER2 | P06734 | 3/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099126 | 0.87 | MMP1 (0.69) | MMP9MMP2MMP7MMP12MMP13 | |
| SCHEMBL6804766 | 0.87 | MMP9 (0.64) | MMP9MMP2MMP7MMP12MMP13 | |
| SCHEMBL4421988 | 0.85 | MMP2 (0.79) | MMP9MMP2MMP7MMP12MMP13 | |
| SCHEMBL16460505 | 0.80 | CTSS (0.62) | RENAPP | |
| SCHEMBL29830619 | 0.80 | CTSS (0.62) | RENAPP | |
| SCHEMBL16460506 | 0.80 | CTSS (0.62) | RENAPP | |
| SCHEMBL27573505 | 0.79 | MMP1 (0.70) | MMP9MMP2MMP7MMP12MMP13 | |
| SCHEMBL4634107 | 0.79 | MMP1 (0.70) | MMP9MMP2MMP7MMP12MMP13 | |
| SCHEMBL4634106 | 0.79 | MMP1 (0.70) | MMP9MMP2MMP7MMP12MMP13 | |
| SCHEMBL4420997 | 0.78 | MMP9 (0.64) | MMP9MMP2MMP7MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237881-A1 | HERBICIDAL HALOGENALKYL-SUBSTITUTED 3-(4,5-DIHYDROISOXAZOL-3-YL)-BENZOYL-CYCLOHEXENONES | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | claimed |
| WO-2001040199-A1 | HERBICIDAL HALOGENALKYL-SUBSTITUTED 3-(4,5-DIHYDROISOXAZOL-3-YL)-BENZOYL-CYCLOHEXENONES | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-07 | — | — | WO | claimed |
| US-6790834-B1 | Cytostatic agents | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 2004-09-14 | — | — | US | disclosed |
| US-6462023-B1 | SUCH AS 2-HYDROXY-HYDROXYCARBAMOYL-METHYL)-4-METHYL-PENTANOYLAMINE)-2-PHENYL -ETHANOIC ACID CYCLOPENTYL ESTER; INHIBITING HYPERPROLIFERATIVE TUMOURGENIC CELLS SUCH AS MELANOMA AND/OR LYMPHOMA CELLS | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 2002-10-08 | — | — | US | disclosed |
| EP-0925278-B1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARM (GB) | 2002-07-17 | — | — | EP | disclosed |
| US-6169075-B1 | ANTITUMOR AGENT INHIBITING THE PROLIFERATION OF A RANGE OF RAPIDLY DIVIDING TUMOUR CELLS LIKE MELANOMA AND/OR LYMPHOMA CELLS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-01-02 | — | — | US | disclosed |
| EP-0925278-A1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011063-A1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |