SCHEMBL6803094

SCHEMBL6803094

CS(=O)(=O)Nc1c(N)cc(N)cc1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 3/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
EP300 Q09472 1/20 0.35
KAT2B Q92831 1/20 0.35
KAT8 Q9H7Z6 1/20 0.35
ADRA2A P08913 2/20 0.34
ADRA2B P18089 2/20 0.34
ADRA2C P18825 2/20 0.34
ADRA1A P35348 2/20 0.34
GAA P10253 2/20 0.33
MAPT P10636 1/20 0.32
HSD17B1 P14061 2/20 0.32
HSD17B2 P37059 2/20 0.32
PIK3CB P42338 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6807722 0.78 CYTH2 (0.54) CA12CA1CA2CA9GAA
SCHEMBL6800198 0.77 LMNA (0.43) ADRB3CA12CA1CA2CA9
SCHEMBL6806686 0.74 EP300 (0.42) ADRB3CA12CA1CA2CA9
SCHEMBL6573116 0.70 EP300 (0.50) ADRB3EP300KAT2BKAT8ADRA2A
Hydrochloric Acid SCHEMBL7160191 0.69 EP300 (0.49) ADRB3EP300KAT2BKAT8ADRA2A
SCHEMBL11641920 0.67 PIK3CB (0.49) CA12CA1CA2CA9PIK3CB
SCHEMBL23226730 0.67 ADRB3 (0.56) ADRB3EP300KAT2BKAT8ADRA2A
SCHEMBL5706546 0.67 CA12 (0.52) CA12CA1CA2CA9EP300
SCHEMBL10941982 0.67 CA12 (0.52) CA12CA1CA2CA9EP300
SCHEMBL10931553 0.67 SNCA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed