SCHEMBL6807722

SCHEMBL6807722

Nc1cc(N)c(NS(=O)(=O)c2ccccc2)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYTH2 Q99418 2/20 0.54
HTR6 P50406 1/20 0.50
KEAP1 Q14145 1/20 0.50
G6PD P11413 1/20 0.50
POLB P06746 2/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
FFAR4 Q5NUL3 3/20 0.49
GAA P10253 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HTT P42858 2/20 0.48
GFER P55789 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
ERBB2 P04626 1/20 0.47
HSP90AA1 P07900 1/20 0.47
HSP90AB1 P08238 1/20 0.47
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6807829 0.81 G6PD (0.56) CYTH2HTR6KEAP1G6PDPOLB
SCHEMBL6807255 0.80 KMT2A (0.51) CYTH2POLBKMT2AMEN1GAA
SCHEMBL6803094 0.78 ADRB3 (0.36) KEAP1KMT2AMEN1GAAALDH1A1
SCHEMBL4050412 0.76 ERBB2 (0.68) HTR6KEAP1POLBKMT2AMEN1
SCHEMBL6817587 0.74 KEAP1 (0.56) CYTH2HTR6KEAP1POLBKMT2A
SCHEMBL11498348 0.73 CYTH2 (0.55) CYTH2HTR6KEAP1KMT2AMEN1
SCHEMBL8016507 0.73 GAA (0.69) CYTH2HTR6KEAP1POLBKMT2A
SCHEMBL16274152 0.73 GAA (0.57) CYTH2POLBKMT2AMEN1FFAR4
SCHEMBL10596760 0.70 KMT2A (0.50) POLBKMT2AMEN1GAAALDH1A1
SCHEMBL6806791 0.70 MEN1 (0.54) POLBKMT2AMEN1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed