Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669371 | 0.86 | EP300 (0.48) | EP300KAT2BKAT8HSD17B1HSD17B2 | |
| SCHEMBL6807829 | 0.81 | G6PD (0.56) | KEAP1CA12CA1CA2CA9 | |
| SCHEMBL11869206 | 0.75 | TSHR (0.44) | ALOX15TSHRCA12CA1CA2 | |
| SCHEMBL6803094 | 0.74 | ADRB3 (0.36) | EP300KAT2BKAT8HSD17B1HSD17B2 | |
| SCHEMBL12262050 | 0.74 | KEAP1 (0.41) | TSHRKEAP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6806548 | 0.73 | ALDH1A1 (0.43) | EP300KAT2BKAT8TSHRKEAP1 | |
| SCHEMBL11022909 | 0.72 | HDAC1 (0.49) | ALOX15TSHRCA12CA1CA2 | |
| SCHEMBL4964367 | 0.70 | ALOX15 (0.48) | EP300KAT2BKAT8ALOX15TSHR | |
| SCHEMBL9584262 | 0.70 | ALOX15 (0.48) | ALOX15TSHRCA12CA1CA2 | |
| SCHEMBL7254610 | 0.69 | TSHR (0.43) | ALOX15TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | claimed |
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | claimed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | claimed |
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | disclosed |
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | disclosed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | disclosed |