Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500070 | 0.87 | SLC6A3 (0.69) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL68818 | 0.87 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL708402 | 0.84 | SLC6A3 (0.69) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL249 | 0.83 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL9536220 | 0.82 | SLC6A3 (0.71) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL6638700 | 0.82 | LTB4R2 (0.52) | LTB4R2ATMCDC25B | |
| SCHEMBL31318316 | 0.82 | SLC6A3 (0.78) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL1775832 | 0.81 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL27843639 | 0.81 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL29066698 | 0.81 | SMN1; SMN2 (0.39) | SLC6A3SLC6A4SLC6A2ALDH1A1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | SLC6A3 4303/4885SLC6A4 4228/4885SLC6A2 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.