Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032670 | 0.90 | ALOX15 (0.44) | ALOX15TSHRCASP1L3MBTL1HPGD | |
| SCHEMBL6803362 | 0.83 | ALOX15 (0.49) | ALOX15TSHRCASP1L3MBTL1HPGD | |
| SCHEMBL7032673 | 0.81 | ALOX15 (0.46) | ALOX15TSHRCASP1L3MBTL1HPGD | |
| SCHEMBL7240741 | 0.79 | ALOX15 (0.44) | ALOX15TSHRCASP1L3MBTL1HPGD | |
| SCHEMBL6463431 | 0.76 | CTSL (0.56) | — | |
| SCHEMBL6807151 | 0.76 | TP53 (0.38) | HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6802148 | 0.74 | NPC1 (0.57) | ALOX15TSHRCASP1L3MBTL1HPGD | |
| SCHEMBL6802848 | 0.73 | CTSS (0.61) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6807038 | 0.73 | CTSS (0.61) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7028150 | 0.73 | CTSS (0.61) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730671-B2 | ENZYME INHIBITOR TREATING AUTOIMMUNE DISEASES, ALZHEIMER'S DISEASE, ATHEROSCLEROSIS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-05-04 | — | — | US | disclosed |