Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | APOB | P04114 | 3/20 | 0.46 |
| ▸ | MTTP | P55157 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665172 | 0.89 | GAA (0.54) | GAAPOLBKDM4EALDH1A1MAPT | |
| SCHEMBL6804465 | 0.88 | L3MBTL1 (0.52) | GAAPOLBKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6803617 | 0.87 | L3MBTL1 (0.51) | GAAPOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL6662843 | 0.86 | SLC2A1 (0.49) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL6802225 | 0.86 | MAOB (0.44) | GAAPOLBKDM4EALDH1A1MAPT | |
| SCHEMBL6803227 | 0.84 | APOB (0.48) | MEN1KMT2ALMNAAPOBMTTP | |
| SCHEMBL6645543 | 0.83 | MTTP (0.61) | GAAKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL6808697 | 0.82 | MAPT (0.49) | POLBALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6803931 | 0.82 | MTTP (0.60) | GAAKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL6662272 | 0.79 | L3MBTL1 (0.51) | GAAKDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | GAA 2694/4885POLB 1962/4885KDM4E 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.