SCHEMBL6804465

SCHEMBL6804465

Cc1ccc(-c2ccccc2C(=O)Nc2ccc3c(c2)CCN3)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.52
LMNA P02545 1/20 0.49
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
ATM Q13315 1/20 0.46
TP53 P04637 1/20 0.46
APOB P04114 5/20 0.46
MTTP P55157 5/20 0.46
AVPR2 P30518 1/20 0.45
CHRNB2 P17787 1/20 0.45
CHRNB4 P30926 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA4 P43681 1/20 0.45
CREBBP Q92793 1/20 0.45
CFTR P13569 1/20 0.44
GAA P10253 2/20 0.44
CYP2C9 P11712 1/20 0.44
TSHR P16473 1/20 0.44
KDM4E B2RXH2 1/20 0.44
HTT P42858 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6803617 0.99 L3MBTL1 (0.51) L3MBTL1LMNAKMT2AMEN1ATM
SCHEMBL6662843 0.89 SLC2A1 (0.49) L3MBTL1LMNAKMT2AMEN1ATM
SCHEMBL6803364 0.88 GAA (0.61) L3MBTL1LMNAKMT2AMEN1ATM
SCHEMBL6662272 0.88 L3MBTL1 (0.51) L3MBTL1LMNAKMT2AMEN1ATM
SCHEMBL6803227 0.87 APOB (0.48) L3MBTL1LMNAKMT2AMEN1ATM
Hydrochloric Acid SCHEMBL6664266 0.87 L3MBTL1 (0.50) L3MBTL1LMNAKMT2AMEN1ATM
SCHEMBL6645543 0.86 MTTP (0.61) LMNATP53APOBMTTPGAA
Hydrochloric Acid SCHEMBL6803931 0.85 MTTP (0.60) LMNATP53APOBMTTPGAA
SCHEMBL6808697 0.85 MAPT (0.49) LMNAKMT2AMEN1ATMTP53
SCHEMBL6802225 0.84 MAOB (0.44) TP53APOBMTTPGAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040157866-A1 Amide compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040157866-A1 Amide compounds APOB, NR1H2, NR1H3 L3MBTL1 1486/4885LMNA 956/4885KMT2A 1496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.