Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC12A2 | P55011 | 1/20 | 0.44 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800199 | 0.93 | MAPT (0.44) | AVPR2AVPR1AMAPTRXFP1NPC1 | |
| SCHEMBL6800495 | 0.91 | MTTP (0.47) | MAPTALDH1A1LMNATP53 | |
| SCHEMBL6801577 | 0.91 | MAPT (0.43) | AVPR2AVPR1AMAPTNPC1ALDH1A1 | |
| SCHEMBL6808866 | 0.89 | SLC12A2 (0.46) | SLC12A2WNK1AVPR2AVPR1AMAPT | |
| SCHEMBL6801575 | 0.85 | MAPT (0.53) | SLC12A2WNK1AVPR2AVPR1AMAPT | |
| SCHEMBL6670037 | 0.84 | AVPR2 (0.43) | AVPR2AVPR1AMAPTNPC1ALDH1A1 | |
| SCHEMBL6668952 | 0.84 | LMNA (0.41) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6804640 | 0.83 | SMO (0.50) | AVPR2AVPR1AMAPTRXFP1LMNA | |
| SCHEMBL6798990 | 0.82 | MAPT (0.43) | AVPR2AVPR1AMAPTRXFP1NPC1 | |
| SCHEMBL6804824 | 0.82 | CASP3 (0.49) | AVPR2AVPR1AMAPTRXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | SLC12A2 1219/4885WNK1 3817/4885AVPR2 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.