Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 8/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503424 | 0.83 | ALOX15 (0.44) | ALOX15ACLY | |
| SCHEMBL6803529 | 0.82 | ALOX15 (0.43) | ALDH1A1ALOX15ACLYPI4KB | |
| SCHEMBL6527791 | 0.82 | ALOX15 (0.44) | ALOX15ACLY | |
| SCHEMBL7113047 | 0.79 | ALOX15 (0.45) | ALOX15ACLY | |
| SCHEMBL7113050 | 0.79 | ALOX15 (0.45) | ALOX15ACLY | |
| SCHEMBL6496384 | 0.78 | ALOX15 (0.53) | ALOX15ACLY | |
| SCHEMBL6496010 | 0.77 | ACLY (0.63) | ALDH1A1ALOX15ACLY | |
| SCHEMBL6502463 | 0.77 | ACLY (0.59) | ALDH1A1ACLY | |
| SCHEMBL6502511 | 0.77 | ACLY (0.46) | ALOX15ACLY | |
| Hydrochloric Acid SCHEMBL6501856 | 0.76 | ACLY (0.45) | ALOX15ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053983-A1 | 1, 2, 4-tribsubstituted benzenes as inhibitors of 15-lipoxygenase | BARVIAN NICOLE CHANTEL (US) | 2004-03-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053983-A1 | 1, 2, 4-tribsubstituted benzenes as inhibitors of 15-lipoxygenase | ALOX15, ALOX5, ALOX15B | ALDH1A1 894/4885MAPK1 1497/4885PTK2B 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.