Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642121 | 0.87 | SLC6A3 (0.60) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL8180022 | 0.84 | CYP46A1 (0.58) | MAPTCYP46A1ALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL6803026 | 0.83 | CFTR (0.51) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL6804716 | 0.83 | MCL1 (0.46) | MAPTALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL9423312 | 0.80 | TDP1 (0.59) | MAPTCYP46A1ALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL30571934 | 0.80 | TDP1 (0.59) | MAPTCYP46A1ALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL8762164 | 0.77 | CA12 (0.47) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL18015088 | 0.76 | KDM4E (0.47) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL30966775 | 0.76 | KDM4E (0.47) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL5535848 | 0.76 | SLC6A3 (0.65) | MAPTCYP46A1ALDH1A1SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | GABRG2 3902/4885GABRB3 2730/4885GABRA3 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.