Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | APOB | P04114 | 2/20 | 0.45 |
| ▸ | MTTP | P55157 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804281 | 0.88 | KIF11 (0.55) | KIF11TRPV1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL6808886 | 0.84 | TRPV1 (0.48) | TRPV1CYP3A4APOBMTTPKDM4E | |
| SCHEMBL6803896 | 0.77 | APOB (0.51) | APOBMTTPKDM4E | |
| Hydrochloric Acid SCHEMBL6804654 | 0.77 | APOB (0.51) | APOBMTTPKDM4E | |
| SCHEMBL6490383 | 0.75 | PTGS1 (0.58) | KIF11TRPV1CYP3A4CYP2C9APOB | |
| SCHEMBL6500905 | 0.74 | TRPV1 (0.50) | TRPV1CYP3A4CYP2C9APOBMTTP | |
| SCHEMBL24508865 | 0.74 | CYP2C9 (0.52) | TRPV1CYP3A4CYP19A1CYP2C9KMT2A | |
| SCHEMBL31423391 | 0.73 | CYP3A4 (0.56) | KIF11TRPV1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL4596430 | 0.73 | KIF11 (0.59) | KIF11TRPV1 | |
| SCHEMBL6687830 | 0.73 | P2RX1 (0.48) | TRPV1CYP3A4CYP2C9APOBMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123039-A1 | ALDEHYDE DEHYDROGENASE INHIBITORS AND THEIR THERAPEUTIC USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2022-06-16 | — | — | WO | disclosed |
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | KIF11 4663/4885TRPV1 2399/4885CYP3A4 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.