Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884015 | 0.76 | GRM5 (0.39) | ALDH1A1KDM4EPTGER4 | |
| SCHEMBL29958007 | 0.72 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL1133921 | 0.71 | KDM4E (0.44) | ALDH1A1KDM4E | |
| SCHEMBL29958037 | 0.71 | CDK4 (0.40) | ALDH1A1 | |
| SCHEMBL4757593 | 0.69 | LMNA (0.40) | ALDH1A1KDM4E | |
| SCHEMBL29958427 | 0.69 | ACACB (0.38) | ALDH1A1 | |
| SCHEMBL29955576 | 0.68 | ALDH1A1 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL29954362 | 0.68 | ESR1 (0.44) | ALDH1A1 | |
| SCHEMBL789028 | 0.67 | — | — | |
| SCHEMBL29953824 | 0.67 | HCAR3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224958-A1 | Pyridopyrimidinone derivatives for treatment of neurodegenerative disease | BOOTH RICHARD JOHN (US) | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224958-A1 | Pyridopyrimidinone derivatives for treatment of neurodegenerative disease | CDK4, CDKL1, CCNT1 | ALDH1A1 1162/4885KDM4E 1816/4885PTGER4 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.