Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | FURIN | P09958 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027612 | 0.89 | LTA4H (0.58) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL8076305 | 0.89 | LTA4H (0.58) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL29458645 | 0.89 | LTA4H (0.58) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL13899983 | 0.87 | MEN1 (0.58) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL6293835 | 0.86 | ESR2 (0.57) | ESR1ESR2ALDH1A1HSD17B1HSD17B2 | |
| SCHEMBL28419866 | 0.85 | LTA4H (0.67) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL70648 | 0.85 | LTA4H (0.67) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL9385056 | 0.85 | LTA4H (0.67) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL37670120 | 0.85 | LTA4H (0.67) | LTA4HNR1H2BAXESR1ESR2 | |
| SCHEMBL4569951 | 0.85 | SMN1; SMN2 (0.60) | LTA4HMEN1KMT2AALDH1A1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103881106-A | Preparation method for titanium nanometer high-polymer alloy oilwell pipe coating material | JIANGSU JINLING SPECIAL PAINT CO LTD | 2014-06-25 | — | — | CN | claimed |
| CN-103819683-A | A novel titanium nanometer polymer alloy material and a preparation method thereof | JIANGSU JINLING SPECIAL PAINT CO LTD | 2014-05-28 | — | — | CN | claimed |
| CN-102585203-A | Halogen-benzene lateral group replaced polyarylether flame retardant material and preparation method thereof | UNIV JILIN | 2012-07-18 | — | — | CN | claimed |
| US-20040142976-A1 | Pyridylfuran and pyridylthiophene compounds | PFIZER INC. | 2004-07-22 | — | — | US | claimed |
| US-20020022729-A1 | Pyridylfuran and pyridylthiophene compounds | KAWAI AKIYOSHI (JP) | 2002-02-21 | — | — | US | claimed |
| EP-0853083-B1 | Pyridylfuran and pyridylthiophene compounds and pharmaceutical use thereof | PFIZER (US) | 2001-09-12 | — | — | EP | claimed |
| EP-0853083-A1 | Pyridylfuran and pyridylthiophene compounds and pharmaceutical use thereof | PFIZER INC. (US) | 1998-07-15 | — | — | EP | claimed |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| CN-103881109-A | Titanium nano macromolecule alloy base material as well as preparation method and equipment thereof | JIANGSU JINLING SPECIAL PAINT CO LTD | 2014-06-25 | — | — | CN | disclosed |
| CN-103881106-A | Preparation method for titanium nanometer high-polymer alloy oilwell pipe coating material | JIANGSU JINLING SPECIAL PAINT CO LTD | 2014-06-25 | — | — | CN | disclosed |
| CN-103819683-A | A novel titanium nanometer polymer alloy material and a preparation method thereof | JIANGSU JINLING SPECIAL PAINT CO LTD | 2014-05-28 | — | — | CN | disclosed |
| CN-103130616-A | Preparing method for fluorine-containing monomer synthesis and nanometer aluminum oxide modified fluorine-containing polyaryletherketone | JIANGSU JINLING SPECIAL PAINT CO LTD | 2013-06-05 | — | — | CN | disclosed |
| EP-0790981-B1 | ARYLOXYCYCLOALKENYL AND ARYLOXYIMINOCYCLOALKENYLHYDROXYUREAS AS 5-LIPOXYGENASE INHIBITORS | PFIZER (US) | 1999-09-08 | — | — | EP | disclosed |
| US-5798383-A | Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas | PFIZER INC. (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0853083-A1 | Pyridylfuran and pyridylthiophene compounds and pharmaceutical use thereof | PFIZER INC. (US) | 1998-07-15 | — | — | EP | disclosed |
| EP-0790981-A1 | ARYLOXYCYCLOALKENYL AND ARYLOXYIMINOCYCLOALKENYLHYDROXYUREAS AS 5-LIPOXYGENASE INHIBITORS | PFIZER PHARMACEUTICALS INC. (JP) | 1997-08-27 | — | — | EP | disclosed |
| CN-1131148-A | Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas | PFIZER (US) | 1996-09-18 | — | — | CN | disclosed |
| WO-1996015106-A1 | ARYLOXYCYCLOALKENYL AND ARYLOXYIMINOCYCLOALKENYLHYDROXYUREAS AS 5-LIPOXYGENASE INHIBITORS | PFIZER PHARMACEUTICALS INC. (JP) | 1996-05-23 | — | — | WO | disclosed |
| US-4443248-A | Phenoxyphenoxypropionic acids and derivatives, and their use as herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1984-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | AHR, TYR, CYP1A1 | LTA4H 2812/4885NR1H2 2905/4885BAX 1490/4885 |
| US-20040142976-A1 | Pyridylfuran and pyridylthiophene compounds | MC2R, FCGR2A, OGFR | LTA4H 1449/4885NR1H2 245/4885BAX 930/4885 |
| US-20020022729-A1 | Pyridylfuran and pyridylthiophene compounds | MC2R, CRHR1, NR3C2 | LTA4H 1332/4885NR1H2 220/4885BAX 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.