Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.57 |
| ▸ | ITGAV | P06756 | 18/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.55 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806785 | 0.91 | ITGB3 (0.51) | ITGB3ITGAVITGA2BITGB5HDAC1 | |
| SCHEMBL4641010 | 0.84 | ITGB3 (0.68) | ITGB3ITGAVITGA2BITGB5HDAC1 | |
| SCHEMBL4641327 | 0.80 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5HDAC1 | |
| SCHEMBL6802305 | 0.77 | CDK1 (0.51) | — | |
| SCHEMBL6806782 | 0.76 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5HDAC1 | |
| SCHEMBL6806677 | 0.74 | CDK1 (0.48) | ITGB3ITGAVHDAC1HDAC2 | |
| SCHEMBL6804208 | 0.73 | CDK1 (0.49) | ITGB3ITGAV | |
| SCHEMBL6806539 | 0.73 | BTK (0.43) | — | |
| SCHEMBL6911764 | 0.72 | ADORA1 (0.40) | ITGB3ITGAV | |
| SCHEMBL6810244 | 0.71 | BTK (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |