Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 6/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911764 | 0.91 | ADORA1 (0.40) | ADORA1CDK2CCNE2CCNE1CCNA2 | |
| SCHEMBL6810244 | 0.88 | BTK (0.42) | BTKADORA1CDK2CCNE2CCNE1 | |
| SCHEMBL6805722 | 0.82 | BTK (0.41) | BTKADORA1CDK2CCNA2 | |
| SCHEMBL4640279 | 0.82 | ITGB3 (0.48) | BTKADORA1FLT3 | |
| SCHEMBL4640271 | 0.82 | ITGB3 (0.48) | BTKADORA1FLT3 | |
| SCHEMBL6802305 | 0.79 | CDK1 (0.51) | CDK2CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL6804912 | 0.79 | ITGB3 (0.45) | CDK2CCNE2CCNE1CCNA2CCNA1 | |
| SCHEMBL6811105 | 0.78 | CNR1 (0.44) | CASP1 | |
| SCHEMBL6806677 | 0.77 | CDK1 (0.48) | CDK2CASP1CCNB2CDK1CCNB1 | |
| SCHEMBL6811574 | 0.75 | ITGB3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |