Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 7/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802305 | 0.90 | CDK1 (0.51) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6804208 | 0.88 | CDK1 (0.49) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL4641283 | 0.83 | ITGB3 (0.46) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6911764 | 0.81 | ADORA1 (0.40) | CDK2CASP1ITGB3ITGAV | |
| SCHEMBL6807065 | 0.78 | CDK1 (0.45) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6811574 | 0.78 | ITGB3 (0.45) | ITGB3ITGAV | |
| SCHEMBL6806539 | 0.77 | BTK (0.43) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL4641275 | 0.75 | ITGB3 (0.43) | HDAC1HDAC2ITGB3ITGAVRAB9A | |
| SCHEMBL6807083 | 0.75 | CASP1 (0.37) | CASP1 | |
| SCHEMBL6805087 | 0.74 | ITGB3 (0.57) | HDAC1HDAC2ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |