Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805979 | 0.83 | CNR1 (0.41) | SYKMAPTKLK7KLK5 | |
| SCHEMBL6805722 | 0.82 | BTK (0.41) | SYKCDK2CCNA2MAPTKLK7 | |
| SCHEMBL6810547 | 0.82 | ITGB3 (0.40) | SYKCDK2CCNE2CCNA2CCNE1 | |
| SCHEMBL6807305 | 0.81 | SYK (0.36) | SYKJAK2KLK7KLK5 | |
| SCHEMBL6016455 | 0.80 | HDAC6 (0.43) | SYKMAPTFGFR1FGFR4PPARA | |
| SCHEMBL6016459 | 0.80 | HDAC6 (0.43) | SYKMAPTFGFR1FGFR4PPARA | |
| SCHEMBL6807065 | 0.80 | CDK1 (0.45) | SYKCDK2CCNE2CCNA2CCNE1 | |
| SCHEMBL6804208 | 0.78 | CDK1 (0.49) | SYKCDK2CCNE2CCNA2CCNE1 | |
| SCHEMBL6806785 | 0.78 | ITGB3 (0.51) | — | |
| SCHEMBL7060984 | 0.78 | MAPT (0.37) | SYKJAK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |