Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810244 | 0.95 | BTK (0.42) | BTKCCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL6810237 | 0.83 | ITGB3 (0.46) | BTKCCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL4644200 | 0.83 | BTK (0.42) | BTKCCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL6805719 | 0.83 | BTK (0.42) | BTKCCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL6810232 | 0.83 | ITGB3 (0.46) | BTKCCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL6911764 | 0.83 | ADORA1 (0.40) | CCNA2CDK2ADORA1SYKALDH1A1 | |
| SCHEMBL6806539 | 0.82 | BTK (0.43) | BTKCCNA2CDK2ADORA1 | |
| SCHEMBL6805849 | 0.82 | SYK (0.42) | CCNA2CDK2KLK7KLK5SYK | |
| SCHEMBL6805979 | 0.81 | CNR1 (0.41) | KLK7KLK5SYKALDH1A1GAA | |
| SCHEMBL6810547 | 0.79 | ITGB3 (0.40) | CCNA2CDK2ADORA1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |