Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 7/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | IARS1 | P41252 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804208 | 0.84 | CDK1 (0.49) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6802305 | 0.81 | CDK1 (0.51) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6805849 | 0.80 | SYK (0.42) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6806677 | 0.78 | CDK1 (0.48) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6805722 | 0.77 | BTK (0.41) | CDK2MAPK1CCNA2SYKKMT2A | |
| SCHEMBL6807305 | 0.77 | SYK (0.36) | ADORA3SYKADORA2AADORA1 | |
| SCHEMBL6806785 | 0.76 | ITGB3 (0.51) | — | |
| SCHEMBL6810547 | 0.74 | ITGB3 (0.40) | CDK2CCNE2CCNA2CCNE1CCNA1 | |
| SCHEMBL4640030 | 0.74 | TDP1 (0.45) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6807059 | 0.74 | TDP1 (0.45) | CDK1CCNB2CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |